(1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride(Abacavir Intermediate) - Names and Identifiers
(1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride(Abacavir Intermediate) - Physico-chemical Properties
Molecular Formula | C6H11NO.HCl
|
Molar Mass | 149.61858 |
Storage Condition | Inert atmosphere,Room Temperature |
(1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride(Abacavir Intermediate) - Introduction
(1S,4R)-(4-aminocycloent-2-enyl) methanol hydrochloride (also known as AMCHA) is an organic compound with the chemical structure:
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Nature:
AMCHA is a colorless or white solid, relatively stable at room temperature. It is a heterocyclic compound with stereoisomerism. Its melting point is 180-184 ° C, and its solubility is good. It is a basic compound, soluble in water and organic solvents.
Use:
AMCHA in the form of hydrochloride is often used as a pharmaceutical intermediate, especially in the synthesis of antiviral and anticancer drugs. It can also be used in organic synthesis reactions such as carbonylation reactions and condensation reactions.
Method:
The preparation of AMCHA is usually obtained by Amine bonding reaction of cyclopentene methanol. The specific procedure is to react cyclopentene methanol with an appropriate amine (such as ammonia) under basic conditions, and then crystallize and purify the resulting product to obtain AMCHA.
Safety Information:
AMCHA is generally safe under correct use, but it is still a chemical and needs to be handled with caution. Contact with skin, eyes or inhalation of AMCHA dust may cause irritation. It is recommended to use personal protective equipment, such as laboratory gloves and protective glasses, during operation. During handling and storage, AMCHA should be kept away from flammable substances and oxidizing agents. In the process of use, storage and disposal, should comply with the relevant safety procedures and regulations.
Last Update:2024-04-09 15:17:53